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Table 2 Bone density of both groups in metastatic bone before RT (baseline), as well as 3 and 6 months after RT

From: Bone density and pain response following intensity-modulated radiotherapy versus three-dimensional conformal radiotherapy for vertebral metastases - secondary results of a randomized trial

  IMRT group   Within group 3DCRT group   Within group Differences between groups  
n Median SD p-value n Median SD p-value HL 95% CI p-value
All metastases
 HU  Baseline 30 258.5 183.3   30 195.0 125.4   62 5.0–126.0 0.037
 HU T2 20 419.3 232.7   19 300.0 165.7   −59.5 −194.0-59.0 0.232
 HU T3 18 416.8 277.7   12 454.0 185.4   61.5 − 146.0-229 0.641
3 months
 HU T0-T2 20 90.5 134.2 < 0.01 19 35.0 87.1 < 0.01 −25.0 − 86.0-42.0 0.407
 HU T0-T2 (%) 20 24.8 51.0 < 0.01 19 18.5 38.7 < 0.01 −4.5 −25.5-21.9 0.723
6 months
 HU T0-T3 18 124.0 166.0 0.023 12 132.0 157.7 < 0.01 59.0 −73.0-193.0 0.330
 HU T0-T3 (%) 18 33.8 61.6 0.048 12 48.4 70.7 < 0.01 34.0 −20.3-91.1 0.341
  1. The results were presented by absolute and relative values (%) of HU within and between groups as median (Hodges–Lehmann estimate) and IQR