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Table 1 Patient and Tumor Characteristics

From: Clinical outcomes of image-guided proton therapy for histologically confirmed stage I non-small cell lung cancer

Characteristic All Inoperable Operable
No. of patients 55 21 34
Age (y), median (range) 71 (48–88) 81 (65–88) 70 (48–79)
Sex
 Male 32 (58%) 15 (71%) 17 (50%)
 Female 23 (42%) 6 (29%) 17 (50%)
Histology
 Adenocarcinoma 44 (80%) 13 (62%) 31 (91%)
 Squamous cell carcinoma 10 (18%) 8 (38%) 2 (6%)
 NSCLC 1 (2%) 0 (0%) 1 (3%)
ECOG performance status
 0 46 (84%) 12 (57%) 34 (100%)
 1 7 (13%) 7 (33%) 0 (0%)
 2 2 (4%) 2 (10%) 0 (0%)
Clinical stage (UICC 7th)
 Stage IA 33 (60%) 13 (62%) 20 (59%)
 Stage IB 22 (40%) 8 (38%) 14 (41%)
Longest tumor diameter (mm), median (range) 27 (10–50) 27 (14–46) 27 (10–50)
Tumor location
 Center (72.6 Gy(RBE)/22 Fr) 6 (11%) 5 (24%) 1 (3%)
 Periphery (66 Gy(RBE)/10 Fr) 49 (89%) 16 (76%) 33 (97%)
Tumor site
 Upper and middle lobe 41 (75%) 16 (76%) 25 (74%)
 Lower lobe 14 (25%) 5 (24%) 9 (26%)
Smoking
 Yes 23 (42%) 12 (57%) 11 (32%)
 No 32 (58%) 9 (43%) 23 (68%)
  1. Abbreviations, NSCLC unclassified non-small cell lung cancer, ECOG Eastern Cooperative Oncology Group; UICC 7th, Union for International Cancer Control 7th edition, Gy(RBE) grays relative effectiveness, Fr fraction