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Table 1 OAR dose constraints applied for three fraction SABR in this study

From: Stereotactic ablative radiotherapy (SABR) as primary, adjuvant, consolidation and re-treatment option in pancreatic cancer: scope for dose escalation and lessons for toxicity

  D0.035 cc D0.1 cc D10.0 cc D5.0 cc V12 Gy V15 Gy V21 Gy
Duodenum ≤ 22.2 Gy ≤ 11.4 Gy ≤ 16.5 Gy
Stomach ≤ 22.2 Gy ≤ 16.5 Gy
Small Bowel ≤ 25.2 Gy ≤ 17.7 Gy
Liver ≤ 50% ≤ 30%
Kidneys (separate) ≤ 25%
Kidneys (together) ≤ 35%
Spinal cord ≤ 21.0 Gy ≤ 18.0 Gy
  1. Note: For all pancreatic patients treated with ≤ 30 Gy in three fractions, we have since revised our duodenal D0.035 cc constraint to the higher limit of 24 Gy, but additionally now use D1.0 cc < 31.4 Gy