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Table 4 Results of Spearman’s correlation tests between parotid shrinkage and diffusion parameters during treatment

From: Radiation-induced parotid changes in oropharyngeal cancer patients: the role of early functional imaging and patient−/treatment-related factors

Variable at the 10th fraction ∆Vol10fr(%) ∆Volpost(%)
Spearman’s Rho p-value Spearman’s Rho p-value
ADC 0.121 0.285 0.103 0.383
Dt 0.286 0.011 0.289 0.013
F −0.057 0.614 −0.232 0.047
D* −0.114 0.314 0.122 0.299
D* × f −0.153 0.176 −0.013 0.910
∆ADC 0.228 0.042 0.173 0.141
∆Dt 0.319 0.004 0.372 0.001
f 0.022 0.844 −0.242 0.038
∆D* −0.117 0.301 0.192 0.101
∆D* × f −0.119 0.293 0.096 0.416
  1. Statistically significant p-values are bold. Abbreviations: ∆Vol10fr Parotid shrinkage(%) at the 10th fraction, ∆Volpost Parotid shrinkage(%) 8 weeks after RT, ADC Apparent diffusion coefficient, Dt Tissue diffusion coefficient, D* Perfusion-related diffusion coefficient, f(%) Perfusion fraction, D* × f Product of D* by f, ∆ADC ADC variation (%) relative to the pretreatment value (analogously for the other imaging variables)