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Table 3 Multivariable Cox regression analysis of distant metastasis free survival in 282 patients treated with radiotherapy and surgery

From: Molecular signature of response to preoperative radiotherapy in locally advanced breast cancer

Variable Reference vs. level Hazard Ratio (95% CI) p-value
MAP3K4 level (low vs. high) 2.54 (1.42, 4.55) 0.002*
ER/PR status (ER+/PR+ vs. ER-/PR+ or ER+/PR-, ER-/PR-) 1.20 (0.94, 1.52) 0.146
Age (under 40 vs. 40–55, 56–70, over 70) 0.81 (0.53, 1.24) 0.332
Menopause (pre-menopausal vs. postmenopausal) 1.19 (0.58, 2.42) 0.639
T-stage (T1 vs. T2, T3, T4) 1.08 (0.75, 1.55) 0.697
  1. *p-value < 0.01