You are viewing the site in preview mode

Skip to main content


Fig. 4 | Radiation Oncology

Fig. 4

From: A critical review of recent developments in radiotherapy for non-small cell lung cancer

Fig. 4

Reprinted with permission. Theresa L. Whiteside et al. Clin Cancer Res 2016;22:1845–1855. Schematic representation of immune-mediated abscopal effects. The systemic proinflamatory effects of irradiating a tumor mass results in it being ‘hot’, and acting as an ‘in situ tumor vaccine’ against distant non-irradiated tumors. Such a local response could be enhanced by administering immunostimulatory antibodies in order to attain an enhanced systemic effect, thereby exploiting the immune effects of radiotherapy. CTL, cytotoxic T cell; RT, radiotherapy

Back to article page