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Table 3 Spearman’s correlations between post-treatment irradiated kidney volume in percent and continuous variables

From: Renal atrophy after stereotactic body radiotherapy for renal cell carcinoma

  Parameters Correlation of irradiated kidney
Variables Median Range Correlation coefficient P value
V5 (%) 73.7 43.3–91.8 −0.44 0.11
V10 (%) 67.3 34.7–82.5 −0.56 0.03*
V15 (%) 62.5 28.8–67.9 −0.68 < .01*
V20 (%) 53.5 24.1–64.6 −0.76 < .01*
V25 (%) 46.8 20.8–61.1 −0.77 < .01*
V30 (%) 41.9 18.3–55.4 −0.71 < .01*
V40 (%) 33.8 14.5–47.5 −0.65 0.01*
V50 (%) 20.7 6.3–42.1 −0.43 0.12
V60 (%) 13.6 0–35.5 −0.19 0.49
Mean irradiated kidney dose (Gy) 27.5 12.9–37.6 −0.66 < .01*
Pre-SBRT irradiated renal volume (cc) 160.4 99.4–295.5 0.07 0.79
GTV (cc) 14.8 3.0–55.6 0.39 0.16
PTV (cc) 79.8 28.1–146.9 −0.03 0.91
Magnitude of overlap between PTV and kidney volume (cc) 19.8 7.9–50.3 −0.56 0.03*
post-treatment contralateral kidney volume in percent (%, n = 12) 99.3 89.4–109.0 0.65 0.02*
Isocenter dose (Gy) 68.8 50.0–76.4 0.07 0.80
Age (years) 75 58–87 0.03 0.89
Creatinine change ratio (peak value/pre-SBRT) (%) 139.5 105.7–190.0 0.32 0.26
  1. Abbreviations: V n percentage volume of the irradiated kidney receiving at least n dose in Gy, *p < .05