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Table 2 Quality Adjusted Life Expectancies [years] for different types of patients, and two different physician beliefs in the curative ability of lymph node irradiation

From: Personalized treatment planning with a model of radiation therapy outcomes for use in multiobjective optimization of IMRT plans for prostate cancer

Patient preference Age Risk group PO a WP\(^{b}_{65\,\%}\) WP\(^{c}_{20\,\%}\) Optimal choice d
Min-complications 60 intermediate 12.0 11.4 11.0 PO
  60 high 9.4 9.9 8.8 MD
  75 intermediate 7.1 6.7 6.4 PO
  75 high 5.8 5.9 5.3 MD
Population average 60 intermediate 12.3 12.6 12.1 MD
  60 high 9.8 11.1 10.0 WP
  75 intermediate 7.2 7.3 7.1 MD
  75 high 6.0 6.6 6.1 WP
Max life 60 intermediate 12.5 13.1 12.7 WP
  60 high 9.9 11.7 10.5 WP
  75 intermediate 7.3 7.7 7.4 WP
  75 high 6.1 7.0 6.3 WP
  1. aPO = prostate-only RT
  2. b WP65 % = whole pelvic RT assuming a 65% cure rate for occult lymph node disease
  3. c WP20 % = whole pelvic RT assuming a 20% cure rate for occult lymph node disease
  4. dMD = optimal choice depends upon physician belief in efficacy of nodal irradiation
  5. Patients are stratified by age, disease risk group and attitude towards the balance between quantity and quality of life