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Table 5 Results for nine plan groups (3 techniques + 3 MLC) for the evaluated parameters for the meningioma cases (average and standard deviation for five patients): QUANTEC criteria where applicable

From: Impact of MLC properties and IMRT technique in meningioma and head-and-neck treatments

Meningioma Criteria Step–and–shoot IMRT dmlc IMRT VMAT
MLCi2 MLCi2+ Agility MLCi2 MLCi2+ Agility MLCi2 MLCi2+ Agility  
Segmentsa   35.8 ± 10.9 = 36.6 ± 11.5 = 33.8 ± 11.3   158.8 ± 27.5 = 159.4 ± 28.9 = 158.4 ± 24.9   250.4 ± 26.2 = 259.8 ± 25.3 = 26638 ± 28.1 1
MU   480.8 ± 140.9 = 474.4 ± 128.8 < 452.7 ± 124.9 < 577.9 ± 166.3 = 609.3 ± 194.4 = 612.5 ± 175.5 = 625.4 ± 125.4 = 642.0 ± 143.5 = 569.0 ± 95.5 2
Estimated delivery time [s]   290. ± 90.8 + 297.5 ± 92.3 + 242.1 ± 69.9 + 300.9 ± 91.7 + 299.5 ± 101.9 + 252.4 ± 90.5 + 209.4 ± 24.1 + 209.0 ± 26.7 + 132.3 ± 9.1 3
PTV EUD 54 50.8 ± 2.3 < 51.1 ± 1.9 < 50.9 ± 2.2 < 53.2 ± 0.2 < 53.2 ± 0.3 < 53.5 ± 0.3 < 53.3 ± 0.6 < 53.5 ± 0.1 < 53.8 ± 0.2 4
Dmean 54 52.6 ± 0.6 < 52.9 ± 0.5 < 52.9 ± 0.5 < 53.9 ± 0.2 < 53.9 ± 0.2 < 54.2 ± 0.2 < 54.0 ± 0.4 < 54.1 ± 0.1 < 54.3 ± 0.2 5
HIICRU 0.198 ± 0.072 + 0.187 ± 0.073 + 0.198 ± 0.063 + 0.142 ± 0.043 + 0.139 ± 0.045 + 0.124 ± 0.041 + 0.133 ± 0.045 + 0.125 ± 0.027 + 0.111 ± 0.034 6
CI100 % 0.267 ± 0.056 < 0.284 ± 0.056 < 0.323 ± 0.066 < 0.499 ± 0.025 < 0.492 ± 0.027 < 0.590 ± 0.028 < 0.523 ± 0.044 < 0.539 ± 0.045 < 0.638 ± 0.021 7
CI95 % 0.622 ± 0.117 < 0.647 ± 0.102 < 0.647 ± 0.107 < 0.750 ± 0.059 = 0.747 ± 0.057 = 0.766 ± 0.062 = 0.760 ± 0.044 = 0.759 ± 0.057 = 0.768 ± 0.055 8
Brainstem Dmax 54 47.9 ± 10.3 = 48.2 ± 10.4 = 48.2 ± 10.1 = 48.1 ± 10.2 = 48.2 ± 10.3 = 48.3 ± 10.6 = 48.1 ± 10.2 = 48.1 = 10.2 = 48.3 ± 10.1 9
Chiasm 54 53.3 ± 0.7 = 53.5 ± 0.4 = 53.8 ± 0.3 = 53.6 ± 0.4 = 53.7 ± 0.3 = 53.7 ± 0.3 = 53.8 ± 0.3 = 53.8 = 0.2 = 53.8 ± 0.3 10
Opt. nerve left 54 41.7 ± 15.9 = 42.0 ± 16.0 = 42.1 ± 16.0 = 42.1 ± 16.1 = 42.1 ± 16.0 = 42.1 ± 16.1 + 42.1 ± 15.8 = 42.0 = 16.1 = 41.9 ± 16.2 11
Opt. nerve right 54 53.7 ± 0.6 = 53.9 ± 0.2 = 53.8 ± 0.3 = 53.8 ± 0.1 = 53.9 ± 0.1 = 53.8 ± 0.1 = 53.8 ± 0.0 = 53.9 = 0.1 = 53.9 ± 0.1 12
Lens left 4.0 ± 1.3 < 4.1 ± 1.2 < 4.1 ± 1.1 < 4.9 ± 1.0 = 4.7 ± 1.3 = 5.0 ± 1.2 = 5.9 ± 0.3 = 6.1 = 0.0 = 6.0 ± 0.1 13
Lens right 11.1 ± 9.5 = 11.3 ± 10.0 = 11.1 ± 8.8 = 16.0 ± 10.8 = 14.9 ± 10.3 = 14.4 ± 9.8 = 16.7 ± 11.8 = 16.9 = 11.4 = 16.4 ± 10.2 14
Bulb left Dmean 7.9 ± 2.4 = 7.7 ± 2.2 = 7.5 ± 1.7 < 8.4 ± 2.0 = 8.3 ± 2.1 = 8.5 ± 2.2 = 8.9 ± 1.7 = 9.1 = 1.5 = 9.1 ± 1.5 15
Dmax 54 20.0 ± 5.2 = 19.8 ± 5.3 = 20.2 ± 4.5 = 20.5 ± 5.6 = 20.1 ± 4.9 = 21.5 ± 5.6 = 19.3 ± 8.7 = 19.7 ± 8.4 = 20.1 ± 8.0 16
Bulb right Dmean 19.0 ± 7.9 = 19.1 ± 8.0 = 20.1 ± 8.4 = 22.5 ± 10.7 = 21.9 ± 10.3 = 22.4 ± 10.9 = 23.0 ± 11.1 = 23.4 ± 11.4 = 23.2 ± 10.9 17
Dmax 54 40.1 ± 13.4 = 39.7 ± 13.3 = 40.5 ± 12.7 = 41.4 ± 13.9 = 41.5 ± 15.0 = 41.3 ± 14.3 = 41.2 ± 13.9 = 41.1 ± 14.6 = 41.0 ± 14.5 18
Brain Dmax 54 53.9 ± 0.8 < 54.1 ± 0.8 < 54.1 ± 0.9 < 54.6 ± 0.6 < 54.5 ± 0.7 < 54.8 ± 0.7 = 54.7 ± 0.8 < 54.8 ± 0.6 < 54.9 ± 0.6 19
  V12 Gy 43.6 ± 16.4 = 43.7 ± 16.4 = 43.4 ± 15.6 = 43.3 ± 15.7 = 43.6 ± 16.1 = 42.5 ± 16.0 = 43.8 ± 14.8 = 44.6 ± 14.6 = 43.5 ± 13.9 20
    A   B   C   D   E   F   G   H   I  
  1. Arrows indicate if a higher or a lower value gives the better plan. “<”,”+” or “=” indicate whether the result is lower, higher or equal to the VMATAgilty according to comparison α (bold) result on a significance level of 5 %, a for segments: results are compared within each technique to the respective Agility plan according to comparison γ (bold)