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Table 4 Results for nine plan groups (3 techniques + 3 MLC) for the evaluated parameters for the head-and-neck cases (average and standard deviation for five patients): QUANTEC criteria where applicable

From: Impact of MLC properties and IMRT technique in meningioma and head-and-neck treatments

Head and neck Criteria Step–and–shoot IMRT dmlc IMRT VMAT
MLCi2 MLCi2+ Agility MLCi2 MLCi2+ Agility MLCi2 MLCi2+ Agility  
Segmentsa   97.6 ± 18.3 + 85.8 ± 14.0 + 78.2 ± 11.7   16930 ± 2.6 = 16935 ± 2.7 = 171.2 ± 1.1   338.0 ± 56.7 = 353.8 ± 76.6 = 375.0 ± 57.5 1
MU   86.1 ± 150.5 = 742.2 ± 109.3 < 657.2 ± 95.2 < 777.4 ± 65.8 < 803.4 ± 75.9 < 803.9 ± 87.1 = 959.5 ± 98.4 + 983.1 ± 123.1 + 893.8 ± 96.3 2
Estimated delivery time [s]   607.4 ± 92.0 + 571.1 ± 71.2 + 447.2 ± 55.7 + 421.2 ± 30.7 + 420.3 ± 25.0 + 323.2 ± 31.4 + 368.3 ± 28.6 + 361.7 ± 44.7 + 224.4 ± 23.1 3
PTV50 4Gy EUD 50.4 47.7 ± 0.2 < 47.7 ± 0.3 < 47.9 ± 0.5 < 48.8 ± 0.6 < 49.1 ± 0.6 < 49.0 ± 0.4 < 49.5 ± 0.8 < 49.5 ± 0.7 < 50.1 ± 0.5 4
Dmean 52.0 ± 1.6 < 52.1 ± 1.5 < 52.1 ± 1.5 < 52.9 ± 1.6 < 52.9 ± 1.6 < 53.0 ± 1.5 < 53.1 ± 1.8 < 53.1 ± 1.7 < 53.3 ± 1.7 5
HIICRU 0.436 ± 0.041 + 0.435 ± 0.041 + 0.431 ± 0.037 + 0.408 ± 0.031 + 0.399 ± 0.032 + 0.404 ± 0.036 + 0.380 ± 0.032 + 0.382 ± 0.031 + 0.373 ± 0.032 6
CI100 % 0.420 ± 0.098 < 0.433 ± 0.090 < 0.429 ± 0.088 < 0.495 ± 0.075 < 0.507 ± 0.071 < 0.522 ± 0.066 = 0.523 ± 0.106 < 0.521 ± 0.088 < 0.566 ± 0.091 7
CI95 % 0.617 ± 0.040 < 0.629 ± 0.038 < 0.634 ± 0.031 < 0.678 ± 0.027 = 0.684 ± 0.028 = 0689 ± 0.026 = 0.692 ± 0.034 < 0.691 ± 0.031 < 0.711 ± 0.033 8
PTV61.6 Gy EUD 61.6 58.4 ± 1.2 < 58.6 ± 1.0 < 58.9 ± 1.3 < 59.9 ± 0.8 < 60.1 ± 0.9 < 60.3 ± 0.9 = 60.3 ± 1.0 < 60.2 ± 1.0 < 60.7 ± 0.9 9
Dmean 60.3 ± 0.7 < 60.4 ± 0.7 < 60.5 ± 0.8 < 61.2 ± 0.5 < 61.3 ± 0.6 < 61.4 ± 0.6 = 61.4 ± 0.7 < 61.3 ± 0.7 < 61.6 ± 0.6 10
HIICRU 0.175 ± 0.035 + 0.172 ± 0.036 + 0.165 ± 0.040 + 0.140 ± 0.028 + 0.135 ± 0.030 + 0.127 ± 0.033 = 0.128 ± 0.025 + 0.132 ± 0.028 + 0.120 ± 0.027 11
CI100 % 0.322 ± 0.084 < 0.326 ± 0.098 < 0351 ± 0.136 < 0.476 ± 0.113 < 0.501 ± 0.127 < 0.539 ± 0.133 = 0.517 ± 0.149 < 0.502 ± 0.132 < 0580 ± 0.146 12
CI95 % 0.702 ± 0.04 < 0.704 ± 0.032 < 0.725 ± 0.048 = 0.775 ± 0.033 = 0.776 ± 0.033 = 0.779 ± 0.032 = 0.782 ± 0.037 = 0.779 ± 0.036 = 0.787 ± 0.037 13
Spinal cord Dmax 50 35.9 ± 4.5 = 35.4 ± 4.0 = 35.1 ± 3.9 = 36.5 ± 4.9 = 35.5 ± 4.0 = 35.6 ± 4.1 = 36.0 ± 4.1 = 35.7 ± 4.5 = 35.5 ± 3.9 14
Brainstem 52 40.1 ± 2.1 = 39.7 ± 2.1 = 39.8 ± 2.4 = 39.0 ± 2.9 = 39.6 ± 2.4 = 40.5 ± 2.4 = 40.0 ± 3.0 = 39.1 ± 2.8 = 39.7 ± 2.7 15
Plexus ipsilateral 61.6 58.5 ± 5.0 = 58.6 ± 5.6 = 58.6 ± 5.6 = 59.0 ± 5.1 = 59.0 ± 5.2 = 59.0 ± 5.1 = 59.0 ± 5.1 = 59.0 ± 5.2 = 58.9 ± 5.1 16
Plexus contralateral 50.4 51.3 ± 1.1 = 51.0 ± 0.7 = 50.8 ± 1.4 = 50.9 ± 0.5 = 51.1 ± 0.5 = 51.2 ± 0.7 = 51.5 ± 1.0 = 51.5 ± 0.9 = 51.3 ± 0.8 17
Mandibula 61.6 60.3 ± 3.5 = 60.5 ± 3.6 = 60.4 ± 2.6 = 60.8 ± 2.3 = 60.1 ± 1.9 = 61.1 ± 1.9 = 61.4 ± 2.3 = 61.1 ± 2.7 = 61.6 ± 2.4 18
Parotid contralateral Dmean 26 23.9 ± 1.7 < 23.6 ± 2.3 < 23.8 ± 0.8 < 25.3 ± 2.2 = 25.6 ± 1.7 = 25.1 ± 1.6 = 24.8 ± 1.9 = 24.8 ± 1.8 = 25.1 ± 1.7 19
V30 Gy 50 34.2 ± 6.3 = 33.6 ± 7.4 = 33.9 ± 4.5 = 36.3 ± 6.4 = 37.9 ± 5.8 + 36.7 ± 5.4 + 33.8 ± 6.8 = 34.3 ± 6.0 = 34.9 ± 6.0 20
Larynx Dmean 46.7 ± 1.2 < 46.3 ± 1.5 < 47.2 ± 1.0 = 47.2 ± 1.1 = 47.3 ± 0.9 = 47.7 ± 0.9 = 47.4 ± 1.8 = 47.2 ± 1.6 = 47.8 ± 1.5 21
  V50 Gy 14.0 ± 12.3 = 13.9 ± 12.2 = 14.9 ± 15.2 = 16.7 ± 13.5 = 17.7 ± 14.4 = 19.3 ± 14.6 = 18.4 ± 15.4 = 17.5 ± 18.0 = 21.0 ± 18.9 22
    A   B   C   D   E   F   G   H   I  
  1. Arrows indicate if a higher or a lower value gives the better plan. “<”,”+” or “=” indicate whether the result is lower, higher or equal to the VMATAgilty according to comparison α (bold) result on a significance level of 5 %, a for segments: results are compared within each technique to the respective Agility plan according to comparison γ (bold)