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Table 2 shows the relationship between NBT and EBRT dose factor and severe complications

From: The safety and usefulness of neutron brachytherapy and external beam radiation in the treatment of patients with gastroesophageal junction adenocarcinoma with or without chemotherapy

Factors   Fistula Bleeding
CRT Yes 4 4
  No 4 9
NBT dose/F 12 Gy/3 F 2 1
  16 Gy/4 F 1 2
  20 Gy/5 F 4 7
  25 Gy/5 F 1 3
EBRT 40 Gy 2 2
  50 Gy 6 9
  52 Gy   1
  60 Gy   1
Total dose 52-56 Gy 2 1
  60-66 Gy 1 2
  70-75 Gy 5 10
  1. Note: CRT = chemotherapy plus radiotherapy, Total dose = EBRT + NBT dose.
  2. F = fraction, NBT = neutron brachytherapy, EBRT = external beam radiotherapy.