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Table 4 Analysis of factors predicting local tumor control after 2-session SRS (Fine-Gray proportional hazards model)

From: A minimally invasive treatment option for large metastatic brain tumors: long-term results of two-session Gamma Knife stereotactic radiosurgery

Covariate Hazard ratio (95% CI) P value
Prior local treatment 2.48 (0.489-12.5) 0.270
Large tumor volume (> 20 mL) 0.600 (0.119-3.01) 0.530
High cumulative dose (> 30 Gy as D95) 0.261 (0.068-1.01) 0.051
Significant tumor volume decrease at 2nd session 0.087 (0.009-0.832) 0.034
  1. SRS = stereotactic radiosurgery, CI = confidence interval, D95 = the dose 95% of the target volume receives.