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Table 3 Analysis of factors predicting patient survival after 2-session SRS (Cox proportional hazards model)

From: A minimally invasive treatment option for large metastatic brain tumors: long-term results of two-session Gamma Knife stereotactic radiosurgery

Covariate Hazard ratio (95% CI) P value
Young (≤ 65 y/o) 0.591 (0.299-1.17) 0.130
High KPS (≥ 90) 0.803 (0.437-1.48) 0.480
Controlled Extra-CNS disease 0.151 (0.057-0.405) < .001
Short interval from cancer diagnosis to SRS (≤ 12 months) 0.274 (0.127-0.593) 0.001
Single BM 0.330 (0.169-0.656) 0.002
  1. SRS = stereotactic radiosurgery, CI = confidence interval, KPS = Karnofsky performance status, CNS = central nervous system, BM = brain metastasis.