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Table 1 Current dosimetric guidelines and isodose volumes stratified by ENI

From: Different rectal toxicity tolerance with and without simultaneous conventionally-fractionated pelvic lymph node treatment in patients receiving hypofractionated prostate radiotherapy

  Goal1 No ENI ENI p2
Rectum   Mean (±SD)  
V70 <10 cc3 2.1 cc (±1.5 cc) 2.4 cc (± 2.0 cc) 0.369
V60 <10 cc4 8.3 cc (±4.2 cc) 9.2 cc (±5.0 cc) 0.158
V50 <17%4 19.5% (±9.1%) 23.0% (±10.6%) 0.021
V30 <35%4 53.6% (±20.0%) 69.8% (±21.4%) <0.001
Bladder     
V60 <10%4 12.1% (±10.1%) 13.4% (±10.8%) 0.197
V50 <25%4 20.5% (±15.2%) 27.1% (±15.7%) <0.001
V30 <50%4 47.2% (±28.0%) 72.9% (±25.5%) <0.001
  1. 1Current guidlines; treatment planning goals have become more strict since initially implemented. 2Independent samples Kruskal-Wallis test. 3Prioritized greater than PTV coverage. 4Planning goal but less important than PTV coverage. Bolded text indicates a statistically significant difference.