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Table 3 Normal tissue constraints

From: Significance of an increase in the Child-Pugh score after radiotherapy in patients with unresectable hepatocellular carcinoma

  1.8-2.0 Gy per fraction 2.5-3.0 Gy per fraction 4.0-5.0 Gy per fraction
Liver TL-V30Gy < 60%   TL-V20Gy < 60%
Mean dose < 31 Gy Mean dose < 30 Gy Mean dose < 22 Gy
Kidney V18Gy < 33% Mean dose < 16 Gy Mean dose < 13 Gy
Spinal cord D2cc < 45 Gy D2cc < 42 Gy D2cc < 33 Gy
Intestine D2cc < 50 Gy D2cc < 45 Gy D2cc < 35 Gy
  1. Abbreviations: TL total liver, V 30Gy  volume of normal tissue that receives more than 30 Gy, D 2cc  maximal dose to 2 cc of normal tissue.