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Table 2 Protocol treatment goals

From: Phase I study of hypofractionated intensity modulated radiation therapy with concurrent and adjuvant temozolomide in patients with glioblastoma multiforme

Volume Goal 1 Goal 2 Goal 3
PTV 60 Gy to ≥ 95% of the PTV ≤ 20% of the PTV to > 66 Gy ≤ 1% of the PTV to < 54 Gy
Optic Chiasm ≤ 5% to > 47.25 Gy ≤ 33% to 40.5 Gy  
Optic nerves ≤ 5% to > 47.25 Gy ≤ 33% to 40.5 Gy  
Brainstem ≤ 5% to > 52.5 Gy ≤ 33% to 45 Gy  
Spinal cord ≤ 5% to > 42 Gy ≤ 33% to 36 Gy  
Eyes ≤ 5% to > 10.5 Gy ≤ 33% to 9 Gy  
  1. Abbreviations: PTV: planning target volume.