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Table 2 Clinical variables, summary of dosimetric statistics and correlation coefficient (Rs) with radiation-induced late gastro-intestinal toxicity incidence

From: Multivariate normal tissue complication probability modeling of gastrointestinal toxicity after external beam radiotherapy for localized prostate cancer

   Univariate analysis
Characteristic    Rs p-value
Categorical N %   
Age (y)     
  ≤70 19 33.3   
  >70 38 66.7 0.105 .436
Tumor size     
  <T3 48 84.2   
  ≥T3 9 15.8 -0.044 .752
PSA     
  ≤15 35 61.4   
  >15 22 38.6 0.051 .707
Gleason score     
  ≤6 34 59.7   
  >6 23 40.3 0.143 .315
Hormonal therapy     
  Yes 53 7.0   
  No 4 93.0 -0.097 .472
Previous abdominal surgery    
  Yes 26 45.6   
  No 31 54.4 0.025 .854
Diabetes    
  Yes 14 24.6   
  No 43 75.4 -0.058 .670
Smokers     
  Yes 31 54.4   
  No 26 45.6 0.199 .137
Antihypertensive/anticoagulants     
  Yes 37 64.9   
  No 20 35.1 -0.338 .010
Acute GI toxicity     
  Yes 21 36.8   
  No 36 63.2 0.309 .020
Radiation treatment     
  CRT 26 45.6   
  ART 31 54.4 -0.174 .195
Continuous Median (range)    
Dmax (Gy) 76.2 (47.2-79.7)   -0.009 .947
Dmean (Gy) 43.2 (14.9-74.9)   0.242 .035
V30 (%) 67.1 (16.8-100)   0.203 .131
V40 (%) 49.4 (12.3-100)   0.244 .067
V50 (%) 39.8 (8.2-99.1)   0.274 .039
V60 (%) 30.1 (2.6-98.0)   0.282 .034
V65 (%) 27.0 (0.4-98.2)   0.284 .032
V70 (%) 26.8 (0.0-97.0)   0.255 .056
V75 (%) 7.6 (0.0-81.7)   0.068 .615