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Table 4 DVH analysis for OAR of the groups breast, lung and neurocranium for treatment plans created with FF and FFF beams

From: The impact of flattening-filter-free beam technology on 3D conformal RT

Parameter Breast Neurocranium Lung
   OAR  
n 13 11 7
   Left eye  
Mean+SD [Gy] - 8.3 ± 2.4 -
- 7.3 ± 2.4 -
p - 0.000 -
   Right eye  
Mean+SD [Gy] - 9.1 ± 2.4 -
- 8.1 ± 2.4 -
p - 0.000 -
   Ipsilateral lung  
Volume [cm3] Mean+SD [Gy] 1791.2 ± 313.6 - 2018.6 ± 319.2
9.1 ± 1.5 - 17.6 ± 2.8
8.9 ± 1.5 - 17.5 ± 3.2
p 0.000 - 0.700
V20Gy [%] 17.7 ± 3.5 - 43.0 ± 7.1
  17.6 ± 3. 4 - 40.6 ± 9.4
p 0.042 - 0.189
   Contralateral lung  
Volume [cm3] 1660.2 ± 394.7 - 2479.0 ± 806.2
Mean+SD [Gy] 0.6 ± 0.1 - 6.8 ± 4.6
0.5 ± 0.0 - 6.8 ± 3.5
p 0.011 - 0.903
   Heart  
Volume [cm3] 555.1 ± 280.4 - -
Mean+SD [Gy] 2.9 ± 2.0 - 11.0 ± 5.5
2.8 ± 2.1 - 11.8 ± 5.6
p 0.018 - 0.011
  1. FFF results are in bold. VxGy volume receiving at least x Gy. Vx volume receiving at least x % of the prescribed dose, Dx % dose received by at least x % of the volume, Statistical significance is defined for p < 0.01.