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Table 3 DVH analysis for PTV and healthy tissue for treatment plans created with FF and FFF beams

From: The impact of flattening-filter-free beam technology on 3D conformal RT

Parameter Breast Neurocranium Lung PTV Spine metastasis Prostate
n 13 11 7 10 11
Volume [cm3] 922.7 ± 239.4 1329.3 ± 109.3 501.9 ± 318.0 175.7 ± 79.6 211.3 ± 94.9
Mean+SD [Gy] 50.2 ± 0.3 30.9 ± 0.3 50.3 ± 0.2 37.9 ± 0.4 66.6 ± 0.6
50.2 ± 0.4 30.3 ± 0.2 50.5 ± 0.4 38.0 ± 0.3 66.5 ± 0.6
p 0.495 0.000 0.408 0.230 0.622
V95 [%] 89.8 ± 1.6 99.9 ± 0.0 95.4 ± 3.3 98.3 ± 3.3 99.6 ± 0.3
89.1 ± 1.8 99.4 ± 0.3 94.3 ± 2.4 97.7 ± 2.6 99.2 ± 0.3
p 0.166 0.000 0.120 0.280 0.027
V107 [%] 0.0 ± 0.0 0.0 ± 0.0 0.0 ± 0.0 0.0 ± 0.0 0.0 ± 0.0
0.0 ± 0.0 0.0 ± 0.0 0.1 ± 0.3 0.0 ± 0.0 0.0 ± 0.0
p 0.166 0.000 0.234 0.133 0.459
HI 0.15 ± 0.0 0.06 ± 0.0 0.12 ± 0.0 0.10 ± 0.0 0.08 ± 0.0
  0.17 ± 0.0 0.08 ± 0.0 0.13 ± 0.0 0.11 ± 0.0 0.09 ± 0.0
p 0.000 0.000 0.151 0.027 0.023
    Healthy tissue   
V5Gy [%] 7.8 ± 1.1 54.7 ± 10.0 27.6 ± 9.5 10.4 ± 2.4 19.8 ± 8.3
7.7 ± 1.1 54.3 ± 10.0 27.7 ± 8.0 10.2 ± 2.4 20.0 ± 8.2
p 0.006 0.000 0.921 0.341 0.639
V10Gy [%] 6.2 ± 1.0 50.8 ± 9.4 20.0 ± 7.3 6.2 ± 1.7 14.4 ± 6.7
6.2 ± 1.0 50.4 ± 9.4 19.6 ± 6.4 6.1 ± 1.7 14.6 ± 6.5
p 0.963 0.000 0.553 0.202 0.293
  1. FFF results are in bold. VxGy: volume receiving at least x Gy. Vx: volume receiving at least x % of the prescribed dose. Dx %: dose received by at least x % of the volume. Statistical significance is defined for p < 0.01.