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Table 2 Comparison of available studies in the literature

From: Hypofractionated image-guided breath-hold SABR (Stereotactic Ablative Body Radiotherapy) of liver metastases – clinical results

Study Irradiated liver metastases (n) Nominal total dose/single dose (Gy) BED2 (Gy) Lesion size (ccm) Median FU (months) 1-year LC rate (%)
Katz et al., 2007 [21] 69 30-55/2-6 40-73* 0.1-950* 14.5 76
McCammon et al., 2009 [5] 81 3 dose levels: 3 levels*: 2.8-370 8.2  
1.) < 36/12 1.) 39    1.) 40
2.) 36-54/12-18 2.) 39-58    2.) 88
3.) 54/18 3.) 58    3.) 100
Milano et al., 2008 [22] 121 10-20/10-20 16-50 0.2-422 Not stated 57
Goodmann et al., 2010 [23] 40 18-30/18-30 42-100* 0.8-146 17 77
Iwata et al., 2010 [24] 12 50-55/5-5.5 62-71* 0.9-22* 14.5 86
Rusthoven et al., 2009 [25] 63 36-60/12-20 66-150* <113* 16 95
Lee et al., 2009 [26] 68 42-60/7-10 59-100* 1.19-3000 10.8 71
Current series JBH et al. 22 24-60/24-12 44-150 11-419 12 57
  1. BED2 and PTV volumes were calculated by JBH et al. (V = 4/3πr3; median/range) in the cases marked with *.