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Table 4 Results of univariate and multivariate analyses for OS and PFS in patients with glioblastoma or anaplastic astrocytoma

From: Patterns of failure after multimodal treatments for high-grade glioma: effectiveness of MIB-1 labeling index

  Variable Test for favorable status OS PFS
Univariate analysis   P value P value
  PS 0,1 (n = 60) vs. 2,3, and 4 (n = 60) <0.01 <0.01
  Age < 50 (n = 37) vs. 50 (n = 94) 0.04 0.08
  Extent of resection GTR/STR (n = 41) vs. PR/biopsy (n = 90) 0.06 0.37
  Histological grade AA (n = 26) vs. GB (n = 105) 0.08 0.11
  MIB-1 LI < 30 (n = 61) vs. 30 (n = 43) 0.21 0.59
  BED or Radiation dose ≤ 72 GyE (n = 77) vs. > 72 GyE (n = 54) 0.29 0.53
  Gender Male (n = 73) vs. Female (n = 58) 0.73 0.54
  Chemotherapy (CT) ACNU based (n = 55) vs. TMZ based (n = 56) 0.91 0.45
Multivariate analysis    
  PS   <0.01 0.01
  Age   0.04 0.07
  Extent of resection   0.04 0.30
  MIB-1 LI   0.07 0.12