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Table 3 Factors may or may not affect the patterns of failure in patients with glioblastoma or anaplastic astrocytoma

From: Patterns of failure after multimodal treatments for high-grade glioma: effectiveness of MIB-1 labeling index

Patients with glioblastoma        
  MIB-1 (n =58) Extent of surgical removal (n =58) Chemotherapy (n =53)
Sites of < 30 30 P value > 80% < 80% P value ACNU TMZ P value
recurrence        based based  
  n = 30 n = 28   n = 20 n = 38 n = 23 n = 30  
Central 25 15 0.014 15 25 0.47 17 20 0.57
Others * 5 13   5 13   6 10
Patients with anaplastic astrocytoma
  MIB-1 (n =16) Extent of surgical removal (n =16) Chemotherapy (n =13)
Sites of < 30 30 P value > 80% < 80% P value ACNU TMZ P value
recurrence
based based
  n = 13 n = 3   n = 5 n = 11 n = 5 n = 8
Central 9 2 0.93 3 8 0.61 4 6 0.84
Others * 4 1   2 3   1 2  
  1. * Others = In-field + marginal + distant.
  2.  > 80% = GTR or Sub-total, < 80% = Partial/Biopsy.