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Table 3 Apoptosis data obtained after the irradiation of PBL at 1, 2 and 8 Gy

From: Combined low initial DNA damage and high radiation-induced apoptosis confers clinical resistance to long-term toxicity in breast cancer patients treated with high-dose radiotherapy

  Mean ± SD Median (range) Tertiles P
DSB/Gy/DNA unit 1.70 ± 0.83 1.46 (0.63-4.08) 1.28-1.78 0.290
RIA 1Gy 13.33 ± 7.26 12.36 (2.51-29.00) 9.58-15.52 0.971
RIA 2Gy 18.20 ± 7.82 17.79 (4.17-32.08) 14.40-22.43 0.996
RIA 8Gy 29.70 ± 10.05 30.44 (9.02-44.10) 24.83-34.40 0.977
α 13.08 ± 7.21 12.64 (1.64-26.63) 9.91-15.63 0.994
β 7.93 ± 2.68 7.85 (3.18-12.57) 7.14-9.29 0.943
  1. Abbreviations: DSB/Gy/DNA unit = double-strand breaks induced per Gy and per 200 Mbp; RIA = radiation-induced apoptosis at 1, 2 and 8 Gy after 24 hours. α and β are the constants that define the model. P values were obtained after a Kolmogorov-Smirnov test.