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Table 6 Treatment recommendations by risk level

From: Risk factors of distant brain failure for patients with newly diagnosed brain metastases treated with stereotactic radiotherapy alone

Risk factor score summation Crude DBF rate Treatment recommendations
0~1 14.8%, SRT as initial treatment and WBRT ± SRT as salvage treatment for DBF
2~3 50.0%, SRT + close clinical monitoring as initial treatment; if close clinical monitoring is impossible, then WBRT+SRT as initial treatment
4 76.9% WBRT+SRT as initial treatmentt
  1. Risk factors include number of BMs > 1, total target volume > 6 cc, uncontrolled extracranial disease and interval time between the diagnosis of the primary tumor and BM < 60 months, and each risk factor was assigned a score of 1