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Table 1 Patient characteristics

From: Risk factors of distant brain failure for patients with newly diagnosed brain metastases treated with stereotactic radiotherapy alone

Parameters Total (n = 132) No DBF (n = 72) DBF (n = 60)
Sex (male %) 75 (56.8%) 47 (65.3%) 28 (46.7%)
Age (years) 57 (27-87) 58 (38-80) 57 (27-87)
No. of metastases 1 (1-6) 1 (1-4) 2 (1-6)
1 86 (65.2%) 57 (43.2%) 29 (22.0%)
> 1 46 (34.8%) 15 (11.4%) 31 (23.5%)
Total target volume (cc) 4.26 (0.10-57.84) 3.42 (0.23-57.84) 3.45 (0.10-45.47)
> 6 50 (37.9%) 22 (16.7%) 28 (21.2%)
≤ 6 82 (62.1%) 50 (37.9%) 32 (24.2%)
Extracranial disease    
Progressive 91 (68.9%) 43 (32.6%) 48 (36.4%)
Absent or controlled 41 (31.1%) 29 (22.0%) 12 (9.1%)
IT (months) 12 (0-240) 12 (0-240) 13 (0-192)
≥ 60 20 (15.2%) 15 (11.4%) 5 (3.8%)
< 60 112 (84.8%) 57 (43.2%) 55 (41.7%)
KPS score 80 (40-90) 80 (40-90) 70 (50-90)
KPS = 70 45 (34.1%) 18 (13.6%) 27 (20.5%)
KPS ≠ 70 87 (65.9%) 54 (40.9%) 33 (25.0%)
Histologic characteristics    
NSCLC 79 (59.8%) 45 (34.1%) 34 (25.8%)
Melanoma 5 (3.8%) 2 (1.5%) 3 (2.3%)
Breast cancer 15 (11.4%) 8 (6.1%) 7 (5.3%)
RCC 9 (6.8%) 6 (4.5%) 3 (2.3%)
Other 24 (18.2%) 11 (8.3%) 13 (9.8%)
  1. IT, interval time; KPS, Karnofsky performance score; NSCLC, non-small cell lung cancer; RCC, renal cell carcinoma