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Table 3 OER variations with dose per fraction

From: Theoretical analysis of the dose dependence of the oxygen enhancement ratio and its relevance for clinical applications

  Low LET (1 keV/μm) High LET (100 keV/μm)
  Dose (Gy) OER Dose (Gy) OER
   V79 T1   V79 T1
Baseline 2.0 2.16 2.74 1.0 1.70 1.66
Scenario 1 1.0 2.09 (-3%) 3.05 (+11%) 0.5 1.69 (-1%) 1.66 (0%)
(dose painting) 3.0 2.21 (+2%) 2.57 (-6%) 1.5 1.70 (0%) 1.66 (0%)
Scenario 2 0.5 2.05 (-5%) 3.32 (+21%) 0.25 1.69 (-1%) 1.66 (+0%)
(hyper-/hypo-fractionation) 20 2.52 (+17%) 2.14 (-22%) 10 1.77 (+4%) 1.68 (+1%)
  1. The calculations were performed for V79 and T1 cell lines irradiated at p h = 0.2 mmHg with various dose levels. OER values (with respect to p a = 30 mmHg) are given for the baseline as well as for two scenarios of dose painting and hyper- or hypofractionation, along with the relative differences to the baseline situation (in percent).