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Figure 2 | Radiation Oncology

Figure 2

From: Theoretical analysis of the dose dependence of the oxygen enhancement ratio and its relevance for clinical applications

Figure 2

Dose dependence of OER for V79 and T1 cells. Dependence of OER on dose per fraction given to hypoxic cells for V79 (Panels A and B) and T1 cell lines (Panels C and D) at low-LET (Panels A and C) and high-LET (B and D). Solid lines show the model calculations for oxygen partial pressures p h in vivo between 0.01 and 20 mmHg (p a = 30 mmHg). Dashed lines correspond to cell experiments in vitro under extreme hypoxia (p h = 0.01 mmHg, p a = 160 mmHg).

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