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Table 3 Relationship between pathological-complete response at breast and axilla with clinico-pathological factors

From: Concurrent chemo-radiotherapy following neoadjuvant chemotherapy in locally advanced breast cancer

Variable N = 112 pCR % (95% CI) Univariate analysis p Multivariate analysis HR (95% CI) p
Age (years)   0.204  
   >50 64 (54–74)   
   <50 75 (67–83)   
Clinical T stage*   0.218  
   T2 54 (45–62)   
   T3 72 (64–80)   
   T4 75 (67–83)   
Clinical N stage*   0.072  
   N1 59(51–67)   
   N2/N3 78 (70–85)   
Clinical stage*   0.656  
   IIB 66 (58–74)   
   IIIA 66 (58–74)   
   IIIB 75 (67–83)   
Estrogen receptors   0.002 3.8 (0.149–0.087) 0.016
   Negative 81 (74–88)   
   Positive 54 (45–63)   
Progesterone receptors   0.090 1.1 (0.391–3.571) 0.767
   Negative 75 (67–83)   
   Positive 60 (52–68)   
Histological grade†   0.06 0.5 (0.244–1.038,) 0.063
   Low/moderate 60 (52–68)   
   High 76 (68–84)   
  1. Abbreviations: pCR = pathological complete response; 95% CI = 95% confidence interval; HR = hazard ratio.
  2. * 6th edition of the American Joint Committee on Cancer TNM classification and staging system.
  3. † Scarff-Bloom-Richardson (SBR) scale.